In the United States, cancer of the endometrium is the most common cancer of the female reproductive organs. The American Cancer Society estimates for cancer of the uterus in the United States for 2015 are: About 54,870 new cases of cancer of the body of the uterus (uterine body or corpus) will be diagnosed. About 10,170 women will die from cancers of the uterine body. These estimates include both endometrial cancers and uterine sarcomas. Up to 8% of uterine body cancers are sarcomas, so the actual numbers for endometrial cancer cases and deaths are slightly lower than these estimates.
Endometrial cancer is rare in women under the age of 45. Most (about 3 out of 4) cases are found in women aged 55 and over. The average chance of a woman being diagnosed with this cancer during her lifetime is about 1 in 37. There are over 600,000 women who are survivors of this cancer. This cancer is slightly more common in white women, but black women are more likely to die from it.